All news

  • New inflammation inhibitor discovered 2018-11-16 A multidisciplinary team of researchers from Karolinska Institutet, University of Texas, Uppsala University and Stockholm University have developed an anti-inflammatory drug molecule with a new mechanism of action. By inhibiting a certain protein (OGG1), the researchers were able to reduce the signals that trigger an inflammation. The study is published in Science.
  • A radical new way to make DNA 2018-11-01 New research reveals that Mycoplasma pathogens make DNA in a unique way that may protect them from our immune response. The result could provide new avenues to combat the pathogens that utilize this strategy. The study is published today in the scientific journal Nature.
  • Three researchers receive EU-funding from MSCA 2018-10-25 Three researchers at Stockholm University have been awarded funding from Marie Skłodowska Curie (MSCA), which is EU´s Research Mobility Program. The projects are in the fields of biochemistry and biophysics, molecular bioscience and astronomy.
  • New method for the interactions of membrane proteins with ligands and lipids 2018-10-23 Researchers from Stockholm University have developed an assay (GFP-TS) that has enabled them to understand how lipids influence the stability of membrane proteins. This method can further be applied for elucidating the function of orphan membrane proteins and for the development of novel drugs against them.
  • How electric fields in living cells control the currents of life 2018-08-13 In living organisms energy is provided in a process that involves separation of charges across membranes by large membrane-protein complexes. The voltage that is maintained across these membranes is equivalent to an electric field strength of about 100 000 V/cm. How these large field strengths influence the function of the membrane-imbedded protein complexes has until now remained unknown.
  • Three researchers at Stockholm University receive ERC Starting Grants 2018-08-07 Three researchers at Stockholm University, including Alexey Amunts at DBB receive the prestigious Starting Grant from the European Research Council, ERC. Project funding amounts to up to 1.5 million euros each.
  • Protein research facilitates discovery of neurodegenerative diseases 2018-07-20 Since 2015, the research project Protein Quality Control, led by researcher Tara Hessa at the Department of Biochemistry and Biophysics at Stockholm University has been conducted. The research project, which is ongoing until 2020, focuses on mapping the cause of malignant proteins in the cell membrane. The research results can make it easier to detect chronic and neurodegenerative diseases at an early stage.
  • New mechanism to detoxify oxygen radicals 2018-06-28 Superoxide is a reactive oxygen species that causes damage to proteins, lipids and DNA and is implicated in many diseases such as cancer, cardiovascular disease and neurodegenerative disorders.
  • A new puzzle piece to control the aging and age-related diseases 2018-06-27 A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism. The study shows that an increasingly deteriorating communication between the cells' organelles is an important cause of aging. The discovery is the result of a collaboration between five research groups at the Universities of Stockholm and Gothenburg including the research group of Martin Ott at DBB.
  • Robert Daniels have been awarded Teacher of the Year 2018 2018-06-27 Robert Daniels at the Department of Biochemistry and Biophysics will be appointed teacher of the year 2018 for his creativity in teaching, which ables his students to experience and test different biochemical processes.
  • Grant from Bill & Melinda Gates Foundation to investigate sepsis 2018-06-27 By diagnosing infections in a simple and effective way many human lives can be saved. Mats Nilsson, Department of Biochemistry and Biophysics at Stockholm University/SciLifeLab, and his research group have now been granted more than 1 million SEK by the Bill & Melinda Gates Foundation to develop a method for examination of children with sepsis.
  • Astrid Gräslund at DBB has been awarded the prestigious Bror Holmberg-medal 2018-05-24 Astrid Gräslund, Professor Emeritus in Biophysics at Stockholm University, has been awarded the prestigious Bror Holmberg-medal for her outstanding research to map the processes that cause proteins to fold incorrectly in the brain and form senile plaques in for example, patients suffering from Alzheimer's disease. The ceremony takes place at the Chemical Association, Lund University on the 24th of May. (further info in Swedish)
  • The 2018 Cancer Society Junior Investigator Award is granted to Alexey Amunts at DBB 2018-05-24 Amunts from Stockholm University and SciLifeLab is one of the four early career investigators that were selected to receive a six-year research support. “Our research group studies how proteins are synthesized folded and assembled into functional multicomponent membrane complexes that drive the cellular energy production. These processes are reported to be upregulated in cancer,” explains Amunts.
  • Dr. Anna Forsby has been awarded The Björn Ekwall Memorial Award 2018 2018-05-21 Associate professor Anna Forsby, Department of Biochemistry and Biophysics and Swetox is the recipient of the Björn Ekwall Memorial Award for the year 2018 in recognition of her scientific achievements in the field of cellular neurotoxicology and development of non-animal test methods.
  • Small membrane proteins regulate respiration in mitochondria 2018-03-22 Energy conversion in living organisms is carried out by large protein complexes composed of multiple components. Small regulatory proteins control this process by changing the distance between these components and modulating their activities. In a recent publication, the structure of such a small regulatory protein was determined, revealing surprising features that are tightly linked to its function.
  • A biological switch regulates the amounts of DNA building blocks 2018-02-02 The enzyme that produces DNA building blocks continues to amaze. The latest surprise is that the enzyme’s on/off switch is positioned at a completely novel site in some marine bacteria. Evolution has once again used an existing component in a new way.
  • The Novo Nordisk Foundation is awarding the 2018 Novozymes Prize to Gunnar von Heijne. 2018-01-29 He is awarded for his scientific breakthroughs in studies of membrane proteins. The Prize is accompanied by DKK 3 million.
  • The cryoelectron microscope has opened researchers' eyes on a whole new atomic level. 2018-01-22 Alexey Amunts at DBB and SciLifeLab in Solna has been investigating the molecular structure of ribosomes in mitochondria and chloroplasts for years. Now a new opportunity has opened: visualization using cryoelectron microscopy. (Read article in Swedish)
  • Merge of the Departments of Neurochemistry and Biochemistry & Biophysics 2018-01-08 As decided by the University Board on December 1 2017, the Department of Neurochemistry and the Department of Biochemistry & Biophysics has from January 1 2018 merged into one department.
  • Extension grants for Wallenberg Scholars resp. Wallenberg Academy Fellows at DBB 2017-12-07 Knut and Alice Wallenberg Foundation (KAW) have made decisions about grants within two calls.
  • Proof of Concept Grant-Life science to Daniel Daley at DBB 2017-10-24 The Swedish Research Council has taken decisions on applications within Proof of Concept Grant – Life science.
  • Prize to biochemist Pål Stenmark at DBB 2017-10-19 The Board of Directors of Sven and Ebba-Christina Hagberg Foundation has decided to award Pål Stenmark at Stockholm University and Anna Överby Wernstedt at Umeå University the foundations personal prize and a research grant totaling 425,000 SEK each.
  • Wallenberg grant increase knowledge about elementary particles and cells' molecular lives 2017-09-29 How can the microcosm of co-acting protein molecules of the cell be stable and function as well as it does? How can the Higgs boson, against current theories, be so easy? Two research projects at Stockholm University supported by Knut and Alice Wallenberg Foundation, seek the answers.
  • A new Botulinum Neurotoxin discovered 2017-08-03 The first new Botulinum Neurotoxin in almost half a century has been discovered by researchers at Stockholm University and Harvard Medical School. Botulinum toxins are widely used to treat a growing list of medical conditions. The article has been published in Nature Communications.
  • New method helps fighting future pandemics 2017-07-07 By developing a new technique for labeling the gene segments of influenza viruses, researchers now know more about how influenza viruses enter the cell and establish cell co-infections – a major contributing factor to potential pandemic development.
  • Bacteria from hot springs solve mystery of metabolism 2017-06-27 Combustion is often a rapid process, like fire. How can our cells control the burning process so well? The question has long puzzled researchers. Using bacteria from hot springs, researchers from Stockholm University now have the answer.
  • New insights into the toxin behind tetanus 2017-06-27 Tetanus toxin is the neurotoxin that causes lockjaw. Many are vaccinated, but tetanus still kills tens of thousands of people per year worldwide. Researchers from the Department of Biochemistry and Biophysics, led by Dr Pål Stenmark, have now uncovered the poison’s structure. For the first time, the way the poison is constructed has been revealed.
  • 75 million in Wallenberg grant extension to Gunnar von Heijne 2017-05-04 Knut and Alice Wallenberg Foundation decided in April to grant an extension of SEK 75 million to Gunnar von Heijne, professor at the Department of Biochemistry and Biophysics, Stockholm University, and Siv Andersson, professor at the Department of Cell and Molecular Biology, Uppsala University for The activities at Wallenberg Advanced Bioinformatics Infrastructure (WABI).
  • Alexey Amunts receives the 2016 Lennart Nilsson Award 2017-02-10 For his pioneering work in the current “resolution revolution,” Alexey Amunts has received this year’s Lennart Nilsson Award. He is a researcher in the Department of Biochemistry and Biophysics at Stockholm University and head researcher at the Cryo-EM Laboratory at SciLifeLab.
  • Alexey Amunts get support from the Ragnar Söderberg Foundation 2017-02-10 Ragnar Söderberg Fellowships in Medicine are awarded by the Ragnar Söderberg Foundation and supports promising young researchers at the beginning of their career, facilitating the establishment of a research group and enabling independence. The granted researchers get SEK 8 million for 5 years. (Further information in Swedish).
  • Researchers at DBB publish in Nature Chemical Biology on Recycling protein building blocks 2017-02-10 An international team of researchers led by Pedro Teixeira, Beata Kmiec and Elzbieta Glaser from the Department of biochemistry and biophysics, Stockholm University, has used the model plant Arabidopsis thaliana to study the degradation process of peptides generated during biosynthesis of chloroplastic proteins, i.e. targeting peptides, and uncovered an enzymatic cascade that degrades these fragments to single amino acids.
  • ERC Consolidator Grant to Martin Högbom 2017-02-10 Martin Högbom at the Department of Biochemistry and Biophysics, Stockholm University, have been awarded the ERC Consolidator Grant. He and his team will study how proteins uses metals to achieve complex chemical reactions. The aim of the research is to better understand the chemical reactions that among other things are important for the conversion to green industrial processes and green energy systems. (Further information in Swedish)
  • David Drew at DBB leads research on salt transporters 2017-02-10 Researchers from Stockholm University and University of Oxford have examined how and why certain lipids stick together salt transporters found in cell membranes, and why others helps to lubricate their movements. These findings open the possibility to develop new treatments for certain types of cancer and high blood pressure. The results were recently published in the scientific journals Nature and Nature Communications. (Further text in Swedish)
  • Stockholm University announce a sponsored research agreement with Ipsen 2016-08-19 Stockholm University announces that it has initiated a research collaboration on structural studies of novel engineered botulinum toxins with Ipsen, a global specialty driven pharmaceutical group. Under the terms of the agreement, Ipsen will fund research in the laboratory of Associate Prof. Pål Stenmark at the Department of Biochemistry and Biophysics, Stockholm University, with a focus on structural biology, protein design and the biophysical properties of novel engineered botulinum toxins.
  • Insight into bacterial cell division 2016-06-07 One approach to fight bad bacteria is to better understand how they divide and multiply. In each bacterium, a large protein complex – called the divisome – governs cell division. The divisome assembles in the middle of the cell to divide the cell and later disassembles to recycle the proteins. A group of scientists at Stockholm University, together with collaborators at the Okinawa Institute of Science and Technology Graduate University (OIST) showed for the first time how this big protein complex inside living E. coli cells disassembles after each round of division.
  • Grants from the European commission to DBB 2016-06-07 The European commission has decided to fund an international training network that focusses on the molecular mechanisms of mitochondrial gene expression. Among the fourteen groups from Europe are Alexey Amunts and Martin Ott from DBB.
  • Piecing together the cells “elevator-like” mechanism for sodium 2016-06-07 Researchers from Stockholm University have pieced together how sodium is transported into and out of our cells. This could be a potential benefit for the development of novel treatments against some forms of cancer and hypertension. The results are published as an article in the scientific journal Nature Structure and Molecular Biology.


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