Department of Biochemistry and Biophysics

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Recent news

  • Scientists discover how to “sweeten” proteins for drug development 2019-06-03 Scientists led by David Drew at the Department of Biochemistry and Biophysics, Stockholm University have established how a sugar called “sialic acid” is delivered into Golgi organelles. The outcome is likely to be able to engineer cells with a better capacity for sialic acid delivery, which could improve the potency of many drugs that are decorated by sialic acid.
  • Gunnar von Heijne honorary doctor in Valencia 2019-04-08 Gunnar von Heijne, professor at the Department of Biochemistry and Biophysics and director of the cryo-electron microscopy facility at SciLifeLab, has been appointed honorary doctor at the University of Valencia.
  • Molecular basis for the variability of mitoribosomes revealed 2019-02-14 Mitochondrial ribosomes are known to be highly variable across species, but the molecular basis for this phenomenon was not known. The analysis published in Molecular Biology and Evolution uncover a fundamental evolutionary mechanism that drives the increasing diversity. The interdisciplinary study was led by Alexey Amunts in collaboration with researchers from Georgia Institute of Technology and Harvard Medical School.
  • An engineered botulinum toxin with improved medicinal potential 2019-01-17 The botulinum neurotoxin is a common medicine for the treatment of a wide range of neuromuscular disorders, including muscle spasms, overactive bladder, cervical dystonia, and cerebral palsy (CP), as well as chronic migraine, and hyper-sweating. A team from Stockholm University, in collaboration with Ipsen Bioinnovation and Harvard Medical School, has now determined the molecular details of why a botulinum toxin variant, that they have designed, has enhanced receptor-binding properties. This engineered toxin shows great promise as a drug candidate.
  • David Drew receives ERC Consolidator Grant 2018-12-17 David Drew at the Department of Biochemistry and Biophysics, Stockholm University, has been awarded an ERC Consolidator Grant. He and his team will study how the cell maintains a healthy working environment. The aim of the research is to establish how a family of proteins required for transporting nutrients and ions in and out of the cell are being turned on-and-off. The outcome is likely to bring us closer to understanding the role of these transporting machines in the human body for the benefit of human health.
  • Nobel Laureate in Chemistry visited Stockholm University 2018-12-11 George P. Smith, one of the Nobel Laureates in Chemistry 2018, visited Stockholm University and the Department of Biochemistry and Biophysics. He held a lecture for PhD students and answered questions about his research and how his interest in chemistry began.